Clear information, grounded in science.

Frequently asked questions

This section provides answers to the most common questions regarding our products, including the De Simone Formulation (CDS22-formula), other proprietary formulations in our portfolio, clinical background, proper use, storage requirements and product authenticity.

While CDS22-formula represents our flagship formulation, our product range includes additional scientifically developed formulations designed for specific applications. Our goal is to provide transparent, evidence-based information to help you make informed decisions. If you cannot find the answer you are looking for, please contact our team for further assistance.

Product & Purchasing

  • You can purchase our products directly from drdesimone.net. In some regions, selected products may also be available through official local distributors. Availability may vary depending on the formulation and local regulations.

  • We recommend purchasing directly from our official website or authorized distributors. This ensures product authenticity, correct storage conditions and full compliance with our quality standards.

About the De Simone Formulation (CDS22-formula)

  • The De Simone Formulation is a unique blend of specific bacterial
    strains developed by Prof. De Simone, extensively studied and recognized
    globally for its effectiveness in treating various intestinal health
    conditions. It is defined in scientific literature and, contained in CDS22-formula, it represents our flagship formulation.

  • No. While the De Simone Formulation (CDS22-formula) is a core and well-known formulation within our portfolio, not all products contain the De Simone Formulation. Other products are developed with different proprietary formulations, each designed for specific scientific and functional objectives.

  • Yes, there are formats specifically designed for children, including drops and lower-dose sachets. Use in children should always be evaluated by a pediatrician or healthcare professional. Please consult a specialist before administering any probiotic product to minors.

  • Yes, the De Simone Formulation can be taken during antibiotic
    treatment to help maintain gut flora balance. It is generally
    recommended to take probiotics a few hours apart from antibiotics.

  • CDS22-formula is lactose-free, as confirmed by our analyses.
    However, due to the cultivation process of certain microorganisms, the
    product may contain traces of casein and beta-lactoglobulin, which are
    milk proteins.

    If your intolerance is strictly to lactose, our
    product may be suitable for you. However, if you have a hypersensitivity
    to milk proteins, we recommend consulting your doctor or allergist
    before taking it.

  • Yes, the formulation is suitable for vegetarians and is free from any animal-derived ingredients.

Other Products & Formulations

  • No. Each product is developed with its own specific formulation and intended use. Different formulations may have different compositions, mechanisms and recommended applications.

  • Shelf life is indicated on each package. Always check the expiration date and follow recommended storage conditions.

  • Detailed information about composition, intended use and storage conditions is available on each individual product page.

Usage & Dosage

  • Each product page provides information regarding format, concentration and recommended usage. If you are unsure which formulation is most appropriate, please consult your healthcare professional. Our customer support can help guide your choice.

  • Dosage and frequency depend on the specific formulation, format and individual needs. Always follow the instructions provided on the product label or as advised by your healthcare professional.

  • In many cases probiotics are taken alongside antibiotics, but timing and dosage may vary depending on the formulation. Please consult your healthcare professional for personalized guidance.

Special Considerations

  • Although probiotic products are generally well tolerated, the adaptation of the intestinal flora to the bacteria may occasionally cause temporary abdominal bloating. In such cases, we recommend reducing the dosage for a few days. If you experience unexpected symptoms, discontinue use and consult your healthcare professional.

  • There are no specific dietary restrictions when taking our probiotics.
    However, for best results, we recommend maintaining a balanced diet. Please refer to the ingredient list on the product page for allergen and dietary information.

  • Response time varies depending on individual conditions, lifestyle and the specific formulation and dosage used. Some individuals may notice changes within hours or few days, while others may require longer periods.

Storage & Shelf Life

  • Storage requirements vary depending on the formulation and product format. Always follow the storage instructions indicated on the product packaging. Temperature-sensitive products require appropriate handling to preserve stability.

  • Shelf life is indicated on each package. Always check the expiration date and follow recommended storage conditions.

  • Suitability depends on the specific formulation. Please refer to the ingredient list of the product you intend to use.

Our team is here to help.

Still need assistance?

If you could not find the information you were looking for, our customer support team will be happy to assist you. For product-related inquiries, formulation details or specific questions regarding the De Simone Formulation (CDS22-formula) or any of our other proprietary formulations, please contact us directly through our dedicated support page.

We are committed to providing clear, accurate and scientifically grounded assistance.

Contact us