Pacchetto Famiglia -15%: 5× CDS22 (450B o 112B) + 1× CDS22 Gocce per Neonati — 🚀 Spedizione Express GRATUITA

Complete microbiome support for the whole family — from day one and beyond

A combined solution designed to support microbiota balance across different ages and needs, with one consistent formulation.

Special price and free express shipping included.

€118,50 €139,50 Salva 15%
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A structured approach to microbiome support across different life stages.

This bundle combines CDS22-formula Infant Drops for early life with CDS22 capsules or sachets for consistent daily support in older children and adults.

Quantità
What’s included in each family bundle?

💙​ Combo 450

  • 1 box of CDS22 Infant Drops
    (2 bottles, 50 billion per bottle)
  • 5 boxes of CDS22-formula 450B
    (12 sachets per box, 60 sachets total)
  • Free express shipping

💚​​ Combo 112

  • 1 box of CDS22 Infant Drops
    (2 bottles, 50 billion per bottle)
  • 5 boxes of CDS22-formula 112B
    (20 capsules per box, 100 capsules total)
  • Free express shipping

All products in the bundle contain the original De Simone Formulation, adapted into different formats for different ages and usage contexts.

Shipped using packaging designed for temperature-sensitive products, to preserve probiotic viability throughout transport.
Learn more about our shipping standards

Offers and product availability may vary depending on your delivery country.

Please make sure to select your country from the dropdown menu in the header/footer to view the correct prices, shipping options, and terms applied to your cart.

From day 1
For the whole family
Refrigered stability
Pacchetto Famiglia -15%: 5× CDS22 (450B o 112B) + 1× CDS22 Gocce per Neonati — 🚀 Spedizione Express GRATUITA

Pacchetto Famiglia -15%: 5× CDS22 (450B o 112B) + 1× CDS22 Gocce per Neonati — 🚀 Spedizione Express GRATUITA

€118,50 Prezzo regolare €139,50
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Who is it for?


This bundle is designed for families with newborns or infants who may benefit from the gentle format of CDS22 Infant Drops, while older children, teenagers and adults can use CDS22 112B or 450B according to their habits and needs.

It is ideal for regular CDS22 users, for those who want a simpler and more convenient way to stock up, and for families looking for one consistent microbiome approach across different ages.

It is made for people who trust the original De Simone Formulation and want one practical routine that can work for the whole family.


Which combo is right for your family?


Both options include the same CDS22 Infant Drops

and the same original De Simone Formulation.

CDS22-formula packaging with two bottles and a dropper on a beige background
CDS22 Infant Drops are included in every bundle and designed for early-life use and more delicate phases.

What's inside one Drops' box?


Each box of CDS22-formula Drops contains:

  • 2 x 5 ml bottles;
  • 2 droppers;
  • 1 activation key, designed to securely tighten the bottle cap and trigger the release of the bacteria into the liquid.

How to prepare and use the Drops included in this bundle


CDS22-formula Drops are always included in this bundle to support early-life use and more delicate phases, with a format designed for precision, flexibility and ease of administration.

Important notes for the drops' use


Shake before each use to ensure a uniform suspension of the live bacteria.

The drops can be taken pure, directly with the dropper or on a spoon, or diluted in water, milk, yogurt, fruit juice, fruit purée, or any non-hot, non-carbonated liquid.

Always follow the recommended dosage as indicated on the leaflet or as advised by your healthcare professional.

How to use the other CDS22 formats


💙 Sachets (450B)

  • Dissolve in water or non-hot, non-carbonated liquids
  • Can be mixed with yogurt or fruit-based foods
  • Consume immediately after preparation

💚 Capsules (112B)

  • Take the capsule with water
  • It can be opened and mixed with non-hot, non-carbonated liquids or soft foods if needed. Consume immediately after preparation

Always follow the recommended dosage indicated on the leaflet or advised by a healthcare professional.

Full composition

  • Measuring cap: filling agent: maltose,

    a blend of live lactic bacteria:

    Streptococcus thermophilus NCIMB 30438,
    Bifidobacterium breve NCIMB 30441,
    Bifidobacterium animalis subsp. lactis NCIMB 30435,
    Bifidobacterium animalis subsp. lactis NCIMB 30436,
    Lactobacillus acidophilus NCIMB 30442,
    Lactobacillus plantarum NCIMB 30437,
    Lactobacillus paracasei NCIMB 30439,
    Lactobacillus helveticus NCIMB 30440.

    Bottle: MCT oil medium chain triglycerides.

  • Maltose, a blend of live lactic bacteria:

    Streptococcus thermophilus NCIMB 30438

    Bifidobacteriumbreve NCIMB 30441

    Bifidobacterium animalis subsp. lactis NCIMB 30435

    Bifidobacterium animalis subsp. lactis NCIMB 30436

    Lactobacillus acidophilus NCIMB 30442

    Lactobacillus plantarum NCIMB 30437

    Lactobacillus paracasei NCIMB 30439

    Lactobacillus helveticus NCIMB 30440

  • A blend of live lactic bacteria:

    Streptococcus thermophilus NCIMB 30438

    Bifidobacteriumbreve NCIMB 30441

    Bifidobacterium animalis subsp. lactis NCIMB 30435

    Bifidobacterium animalis subsp. lactis NCIMB 30436

    Lactobacillus acidophilus NCIMB 30442

    Lactobacillus plantarum NCIMB 30437

    Lactobacillus paracasei NCIMB 30439

    Lactobacillus helveticus NCIMB 30440

    filling agent: microcrystalline cellulose; hydroxypropylmethylcellulose vegetable capsule; anti-caking agents: fatty acids, magnesium salts of fatty acids.

The same original De Simone Formulation is used across all products in this bundle, ensuring continuity from the very first days of life through later stages.

All products may contain traces of milk.

Formulation standards for all the products:

Gluten Free
Without Preservatives
Non GMO
Vegetarian

Storage and handling


All CDS22-formula products should be stored in the refrigerator to maintain the vitality and potency of the bacteria until expiration.

You can store the product outside the refrigerator at room temperature (up to 25°C) for up to a week without compromising its quality.

Avoid high temperatures (>25°C).

Best before the date indicated on the package.

Drops: once activated, the product is designed to be used within 3 weeks after opening to ensure optimal viability of the probiotic strains.

Same rigorous formulation. Adapted to every stage of life.


Understanding CDS22-formula

Questions parents often ask


Find answers to the most common questions regarding the administration, storage, and benefits of our products. This section is designed to help parents and healthcare professionals use the De Simone Formulation correctly.

  • The recommended daily dose is 1-2 drops per kg of weight up to a maximum of 20 drops per day.

    For older children, capsules or sachets may be used depending on preference and context.

    Sachets 450B: up to 1/2 sachet per day

    Capsule 112B: 1-2 capsules per day

    We always recommend following the instructions on the leaflet or consulting a healthcare professional for personalized guidance.

  • Yes, CDS22-formula Drops are specifically designed for early-life use and can be administered starting from the very first days of life.

  • The drops can be mixed with milk or other liquids, provided they are not hot. High temperatures must be avoided to preserve the integrity of the live bacteria.

  • Yes.

    All products in the bundle should be stored refrigerated at 2–8°C to maintain optimal stability.

    Short periods outside the refrigerator (e.g. during transport) do not affect product quality.

    For Infant Drops, once activated, the product should be used within 3 weeks.

  • Yes.

    The De Simone Formulation has been widely studied and is known for its established safety and tolerability, including in longer-term use.

    The duration of use may vary depending on individual needs and should be evaluated with a healthcare professional.

  • It is possible to take CDS22-formula (all formats) in conjunction with antibiotic therapy given the absence of known interactions of these drugs with the bacteria contained in the product. To maximize the beneficial effect of the probiotic, it is advisable to take CDS22-formula a few hours after the drug. If in doubt, ask your doctor or pharmacist for advice.

  • Although no particular risks associated with the use of CDS22-formula have been highlighted, the adaptation of the intestinal flora to the bacteria it contains can cause transient abdominal swelling. In this case, it is recommended to reduce the dosage of CDS22-formula for a few days.

  • It is gluten-free and lactose-free.

    However, traces of milk may be present due to the culture methods used for some strains. While this is generally not an issue for individuals with lactose intolerance, it may not be suitable for those with a milk protein allergy.

Food supplement notice

CDS22-formula is a food supplement.

It should not be used as a substitute for a varied and balanced diet, a healthy lifestyle, or professional medical advice.

Do not exceed the recommended daily dose.

If you have a medical condition, are taking medication, or have special circumstances such as pregnancy or breastfeeding, consult a qualified healthcare professional.