Both options include the same CDS22 Infant Drops
and the same original De Simone Formulation.
A combined solution designed to support microbiota balance across different ages and needs, with one consistent formulation.
Special price and free express shipping included.
A structured approach to microbiome support across different life stages.
This bundle combines CDS22-formula Infant Drops for early life with CDS22 capsules or sachets for consistent daily support in older children and adults.
All products in the bundle contain the original De Simone Formulation, adapted into different formats for different ages and usage contexts.
Shipped using packaging designed for temperature-sensitive products, to preserve probiotic viability throughout transport.
Learn more about our shipping standards
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This bundle is designed for families with newborns or infants who may benefit from the gentle format of CDS22 Infant Drops, while older children, teenagers and adults can use CDS22 112B or 450B according to their habits and needs.
It is ideal for regular CDS22 users, for those who want a simpler and more convenient way to stock up, and for families looking for one consistent microbiome approach across different ages.
It is made for people who trust the original De Simone Formulation and want
Both options include the same CDS22 Infant Drops
and the same original De Simone Formulation.
Best for families who prefer the sachet format for more structured or higher-intensity support in older children and adults.
Best for families who prefer the practicality and versatility of capsules and 112 billion CFU dosage, for continuity and easy daily use.
What's inside one Drops' box?
Each box of CDS22-formula Drops contains:
CDS22-formula Drops are always included in this bundle to support early-life use and more delicate phases, with a format designed for precision, flexibility and ease of administration.
Fit the activation ring onto the bottle cap to release the powder into the oil.
Twist the cap clockwise until it stops. Now the live bacteria are released from the sealed cap into the oil.
Tap the cap to ensure all the powder falls into the bottle and shake. Make sure the full contents are released before proceeding.
Shake before each use to ensure a uniform suspension of the live bacteria.
The drops can be taken pure, directly with the dropper or on a spoon, or diluted in water, milk, yogurt, fruit juice, fruit purée, or any non-hot, non-carbonated liquid.
Always follow the recommended dosage as indicated on the leaflet or as advised by your healthcare professional.
Always follow the recommended dosage indicated on the leaflet or advised by a healthcare professional.
Measuring cap: filling agent: maltose,
a blend of live lactic bacteria:
Streptococcus thermophilus NCIMB 30438,
Bifidobacterium breve NCIMB 30441,
Bifidobacterium animalis subsp. lactis NCIMB 30435,
Bifidobacterium animalis subsp. lactis NCIMB 30436,
Lactobacillus acidophilus NCIMB 30442,
Lactobacillus plantarum NCIMB 30437,
Lactobacillus paracasei NCIMB 30439,
Lactobacillus helveticus NCIMB 30440.
Bottle: MCT oil medium chain triglycerides.
Maltose, a blend of live lactic bacteria:
Streptococcus thermophilus NCIMB 30438
Bifidobacteriumbreve NCIMB 30441
Bifidobacterium animalis subsp. lactis NCIMB 30435
Bifidobacterium animalis subsp. lactis NCIMB 30436
Lactobacillus acidophilus NCIMB 30442
Lactobacillus plantarum NCIMB 30437
Lactobacillus paracasei NCIMB 30439
Lactobacillus helveticus NCIMB 30440
A blend of live lactic bacteria:
Streptococcus thermophilus NCIMB 30438
Bifidobacteriumbreve NCIMB 30441
Bifidobacterium animalis subsp. lactis NCIMB 30435
Bifidobacterium animalis subsp. lactis NCIMB 30436
Lactobacillus acidophilus NCIMB 30442
Lactobacillus plantarum NCIMB 30437
Lactobacillus paracasei NCIMB 30439
Lactobacillus helveticus NCIMB 30440
filling agent: microcrystalline cellulose; hydroxypropylmethylcellulose vegetable capsule; anti-caking agents: fatty acids, magnesium salts of fatty acids.
The same
All products may contain traces of milk.
Formulation standards for all the products:
All CDS22-formula products should be stored in the refrigerator to maintain the vitality and potency of the bacteria until expiration.
You can store the product outside the refrigerator at room temperature (up to 25°C) for up to a week without compromising its quality.
Avoid high temperatures (>25°C).
Best before the date indicated on the package.
Drops: once activated, the product is designed to be used within 3 weeks after opening to ensure optimal viability of the probiotic strains.
Same rigorous formulation. Adapted to every stage of life.
Find answers to the most common questions regarding the administration, storage, and benefits of our products. This section is designed to help parents and healthcare professionals use the De Simone Formulation correctly.
The recommended daily dose is 1-2 drops per kg of weight up to a maximum of 20 drops per day.
For older children, capsules or sachets may be used depending on preference and context.
Sachets 450B: up to 1/2 sachet per day
Capsule 112B: 1-2 capsules per day
We always recommend following the instructions on the leaflet or consulting a healthcare professional for personalized guidance.
Yes, CDS22-formula Drops are specifically designed for early-life use and can be administered starting from the very first days of life.
The drops can be mixed with milk or other liquids, provided they are not hot. High temperatures must be avoided to preserve the integrity of the live bacteria.
Yes.
All products in the bundle should be stored refrigerated at 2–8°C to maintain optimal stability.
Short periods outside the refrigerator (e.g. during transport) do not affect product quality.
For Infant Drops, once activated, the product should be used within 3 weeks.
Yes.
The De Simone Formulation has been widely studied and is known for its established safety and tolerability, including in longer-term use.
The duration of use may vary depending on individual needs and should be evaluated with a healthcare professional.
It is possible to take CDS22-formula (all formats) in conjunction with antibiotic therapy given the absence of known interactions of these drugs with the bacteria contained in the product. To maximize the beneficial effect of the probiotic, it is advisable to take CDS22-formula a few hours after the drug. If in doubt, ask your doctor or pharmacist for advice.
Although no particular risks associated with the use of CDS22-formula have been highlighted, the adaptation of the intestinal flora to the bacteria it contains can cause transient abdominal swelling. In this case, it is recommended to reduce the dosage of CDS22-formula for a few days.
It is gluten-free and lactose-free.
However, traces of milk may be present due to the culture methods used for some strains. While this is generally not an issue for individuals with lactose intolerance, it may not be suitable for those with a milk protein allergy.
Food supplement notice
CDS22-formula is a food supplement.
It should not be used as a substitute for a varied and balanced diet, a healthy lifestyle, or professional medical advice.
Do not exceed the recommended daily dose.
If you have a medical condition, are taking medication, or have special circumstances such as pregnancy or breastfeeding, consult a qualified healthcare professional.