drdesimone.net is dedicated to preserving and distributing the original De Simone Formulation, while also developing and offering additional scientifically designed formulations for specific clinical and functional needs.

Founded on decades of research led by Prof. Claudio De Simone (MD, FAGA), our work reflects a broader commitment to evidence-based probiotic science and innovation.

Formerly professor of Infectious Diseases (Italy, University of L'Aquila), with a background in gastroenterology, allergology and clinical immunology, his academic career has been marked by a continuous commitment to research, clinical application, and regulatory standards in probiotic development.

Over the years, Prof. De Simone's work contributed to defining quality criteria for strain selection, formulation stability, and evidence-based use of probiotics in the dietary management of gastrointestinal conditions. This scientific approach remains at the core of the original De Simone Formulation today.

Developed by Prof. Claudio De Simone, the original De Simone Formulation has travelled through different markets, brands and scientific milestones. Its identity has been preserved, defended and clarified over time — by the inventor, by the scientific record and by formal attribution.

Today, CDS22-formula makes the original De Simone Formulation available in the EU and UK under its current brand name.

At DrDesimone.net, our commitment goes beyond distribution. We work to ensure that the original De Simone Formulation is preserved according to the scientific specifications defined during its development.

From controlled manufacturing processes to temperature-managed handling, every step reflects the standards of quality, stability, and authenticity that underpin decades of research.

Our goal is to maintain continuity with the original formulation while advancing new scientifically grounded developments, guided by evidence and delivered with responsibility.