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Country:  Italy • EUR
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Crafted to the original Prof. De Simone formulations.

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CDS22-formula: DIFFERENT FORMATS; ONE FORMULATION.

CDS22-formula is available on drdesimone.net in the following formats:

- Sachets with 450 Billion CFU
- Sachets with 225 Billion CFU (Italy only)
- Capsules with 112 Billion CFU
- Drops with 0,5 Billion CFU

Perfect for daily use, during any season (even in summer months — with refrigerated pouch), and shipped with care and Express Delivery (find out more on our shipping standards).

  • 450 Billion CFU
    per sachet

    For those who need to restore gut flora with intensive and long-lasting support.

    Recommended for:

    Chronic dysbiosis (frequent diarrhea or constipation);

    After pharmacological treatments that alter intestinal flora.

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  • 225 Billion CFU
    per sachet

    For those seeking a flexible, well-rounded balance and looking to optimize the gut microbiota’s physiological responses in stressful situations.

    Recommended for:

    Changes in intestinal motility;

    Digestive discomfort associated with periods of change and stress.

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  • 112 Billion CFU
    per capsule

    For those seeking a daily or seasonal routine to support intestinal well-being.

    Recommended for:

    Maintaining the balance of intestinal flora;

    Occasional digestive discomfort.

    Buy Now 

  • 0,5 Billion CFU
    per drop

    For those who want to promote the development and maintenance of their children’s intestinal microbiota from the very first days of life.

    Recommended for:

    Newborns and infants prone to dysbiosis-related intestinal disturbances (colic, unformed stools, abdominal pain);

    Young children during sensitive phases (weaning, starting nursery/daycare) or during and after courses of medication.

    Buy Now 

Why choose CDS22-formula?

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  • De Simone Approved Formula stamp on a white background

    Guaranteed originality

    CDS22-formula is the original De Simone Formulation (DSF), approved and guaranteed by the inventor.

  • Maximum potency

    CDS22-formula offers one of the highest concentrations available on the market.

  • Maximum safety

    • 20+ years of research and use, with no adverse effects reported to the authorities
    • 80+ clinical studies
    • 200+ scientific publications
    • Recognized in the guidelines of the American Gastroenterological Association (AGA) and the European Crohn’s and Colitis Organization (ECCO)
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  • What does CDS22-formula do?

    - Maintains and restores the balance of the intestinal flora


    - Supports the dietary management of acute and chronic intestinal dysbiosis


    - Useful in inflammatory diseases of the colon and rectum


    - Helps reducing bloating, diarrhea, and constipation

  • Does CDS22-formula contain allergens?

    ✓ Gluten-free

    ✓ Peanut-free

    ✓ Corn-starch-free

    ✓ Lactose-free

    ⚠️ Note: may contain traces of milk proteins.


    Additionally, CDS22    -formula is:

    ✓ Vegetarian

    ✓ Preservative-free

    ✓ Non-GMO (contains no genetically modified ingredients)