The 450B formulation behind this Pro Pack
CDS22-formula 450 is designed for individuals experiencing
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Paquete PRO 450: 15 cajas CDS22 450B con 20 % de descuento + 🚀 ENVÍO EXPRESS GRATIS 💥 ¡Nuestra mejor oferta!
15 boxes. Maximum value.
€298,80
€373,50
Precio por unidad
€19,92
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Designed for those who already rely on CDS22-formula 450B and want to maintain continuity over time — with a more convenient price and free express shipping included.
Cantidad
What’s included in this PRO Pack?
- 15 boxes of CDS22-formula 450B
- 180 sachets total
- 450 billion CFU per sachet
- 20% OFF + FREE DHL Express shipping
What is inside each sachet?
- 450 billion CFU per sachet
high-concentration live bacteria blend designed to support even during demanding situations; - the original De Simone Formulation
used for over 25 years in clinical and real-world settings; - 8 selected bacterial strains
known for their established safety and tolerability.
Shipped using packaging designed for temperature-sensitive products, to preserve probiotic viability throughout transport.
Learn more about our shipping standards.
Country-Specific Availability
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180 sachets
450 billion CFU
Refrigered stability
Ideal for...
Strength and harmony: restore your gut flora for lasting balance and well-being.
A structured microbiome approach for demanding situations
CDS22-formula 450 is designed for situations where microbiome support needs to be more consistent and sustained over time.
Its high concentration and defined composition make it suitable for individuals facing intensive, prolonged or recurring intestinal imbalance.
It contains the original De Simone Formulation, a unique probiotic blend studied for over 25 years and used in both clinical research and real-world settings, with an established profile of safety and tolerability, including in more sensitive individuals and in longer-term use.
Simple to use, easy to integrate
How to prepare and use it
CDS22-formula 450 comes in a ready-to-use sachet format.
The contents can be dissolved in water or other non-hot, non-carbonated liquids, including yogurt or fruit juice.
For children, the sachet can also be added to non-hot milk or fruit compote.
Consume immediately after preparation.
Always follow the recommended dosage as indicated on the leaflet or advised by a professional.
Full composition and
A defined multi-strain formulation, developed with precise composition and controlled manufacturing standards.
Maltose, a blend of live lactic bacteria:
Streptococcus thermophilus NCIMB 30438
Bifidobacteriumbreve NCIMB 30441
Bifidobacterium animalis subsp. lactis NCIMB 30435
Bifidobacterium animalis subsp. lactis NCIMB 30436
Lactobacillus acidophilus NCIMB 30442
Lactobacillus plantarum NCIMB 30437
Lactobacillus paracasei NCIMB 30439
Lactobacillus helveticus NCIMB 30440
It may contain traces of milk.
Formulation standards:
Gluten Free
Without Preservatives
Non GMO
Vegetarian
Store in the refrigerator to maintain the vitality and potency of the bacteria until expiration.
You can store the product outside the refrigerator at room temperature (up to 25°C) for up to a week without compromising its quality.
Avoid high temperatures (>25°C).
Best before the date indicated on the package.
The same formulation is available in different formats, depending on individual needs.
Same rigorous formulation.
Drops
Specifically engineered for early life and precision. Suitable from the first days with an easy administration system.
Capsules
Each capsule delivers 112 billion live bacteria from the same De Simone Formulation, in a practical, versatile capsule format designed for everyday convenience.
Sachets
Designed for more intensive phases and daily routine alike, each sachet delivers 450 billion live bacteria for high-level support whenever needed.
Before you decide, here are the most common questions about this PRO Pack
Frequently Asked Questions
Find answers to the most common questions regarding the administration, storage, and benefits of our product. This section is designed to help consumers and healthcare professionals use the De Simone Formulation correctly.
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Because it’s the most convenient way to buy CDS22-formula 450B.
You get:
- 20% savings compared to individual boxes
- free express shipping
- a single purchase instead of multiple reorders
It’s the smart choice for those who already rely on the product and want to stock up.
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The duration of a PRO Pack depends on individual usage.
Based on typical intake ranges of 1 to 2 sachets per day, a pack of 15 boxes (180 sachets total) may last approximately (for one person):
around 6 months at 1 sachet per day
around 3 months at 2 sachets per day
In some specific protocols or under medical supervision, higher daily intakes may be used.
For this reason, duration can vary and should be adapted to individual needs.
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The formulation has been studied for over 25 years and is characterized by a well-established profile of safety and tolerability.
It has been used in both clinical research and real-world settings, including in protocols involving extended use.Duration of use may vary depending on individual needs and should be evaluated with a healthcare professional.
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- Adults and children aged 7 and over: 1–2 sachets per day.
- Children from 3 to 6 years: up to ½ sachet per day.
The dosage may vary depending on individual needs and should always follow the instructions provided or the advice of a healthcare professional.
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CDS22-formula 450 is designed for situations where the intestinal microbiota may require a sustained and structured level of support, such as during periods of prolonged imbalance or intestinal stress.
Individual needs may vary, and professional advice is recommended. -
The duration of use should be based on individual needs or professional medical advice.
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It is possible to take CDS22-formula in conjunction with antibiotic therapy given the absence of known interactions of these drugs with the bacteria contained in the product. To maximize the beneficial effect of the probiotic, it is advisable to take CDS22-formula a few hours after the drug.
If in doubt, ask your doctor or pharmacist for advice.
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There are no known contraindications of CDS22-formula, but it is advisable to consult your doctor before taking any food supplement during pregnancy.
If you are pregnant, breastfeeding, or taking any medications, consult your doctor before using this dietary supplement.
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Yes, this is a refrigerated product that must be stored between 2–8°C.
However, the product can be kept at room temperature (up to 25°C) for limited periods (up to 7 days) without compromising its quality. -
CDS22-formula 450 contains a well-characterized multi-strain formulation with an established profile of safety and tolerability.
Individual responses may vary, and it is advisable to consult a healthcare professional in case of specific conditions. -
Although no particular risks associated with the use of CDS22-formula have been highlighted, the adaptation of the intestinal flora to the bacteria it contains can cause transient abdominal swelling.
In this case, it is recommended to reduce the dosage of CDS22-formula for a few days.
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It is gluten-free and lactose-free.
However, traces of milk may be present due to the culture methods used for some strains. While this is generally not an issue for individuals with lactose intolerance, it may not be suitable for those with a milk protein allergy.
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The contents of the sachet can be dissolved in water or other non-hot, non-carbonated liquids, including yogurt or fruit juice.
If the sachet is not used in one intake, it can be carefully folded, stored in the refrigerator, and consumed later.
Food supplement notice
CDS22-formula is a food supplement.
It should not be used as a substitute for a varied and balanced diet, a healthy lifestyle, or professional medical advice.
Do not exceed the recommended daily dose.
If you have a medical condition, are taking medication, or have special circumstances such as pregnancy or breastfeeding, consult a qualified healthcare professional.
Find CDS22-formula 450B in our bundles and current offers—mix with complementary products and optimize continuity.
✨OFFERTA ESTIVA✨ 2 scatole CDS22 a scelta + 🧊 1 CoolPouch refrigerante (fucsia o lima) + 🚀 Spedizione EXPRESS
€45,00
✨OFFERTA ESTIVA✨ 2 scatole CDS22 a scelta + 🧊 1 CoolPouch refrigerante (fucsia o lima) + 🚀 Spedizione EXPRESS - variante de color: Cal
✨OFFERTA ESTIVA✨ 2 scatole CDS22 a scelta + 🧊 1 CoolPouch refrigerante (fucsia o lima) + 🚀 Spedizione EXPRESS - variante de color: Fucsia
2
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