CDS22-formula
CDS22-formula
CDS22-formula

CDS22-formula

THE ORIGINAL DE SIMONE FORMULATION (DSF)


The clinically studied probiotic blend with 80+ clinical trials and 200+ scientific publicationsrecognized and trusted for 25+ years worldwide.

Developed by Prof. Claudio De Simone, CDS22-formula is built on defined strains and a precisely balanced composition to deliver consistent quality you can rely on.


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Who can benefit?

  • Those experiencing chronic dysbiosis and seeking a high-concentration, well-balanced probiotic solution.
  • Individuals looking to maintain healthy digestion during recurrent or prolonged intestinal stress, including stress linked to emotional well-being.
  • Anyone needing to restore or maintain gut flora balance after pharmacological treatments.

See if it’s a fit for you → take our self-assessment tests

How does it works?

CDS22-formula combines 8 carefully selected bacterial strains, chosen for their biochemical and enzymatic profile, and specifically blended in precise proportions to act synergistically on the physiology of the human gastrointestinal system.
Mucomixx
Mucomixx
Mucomixx

Mucomixx

GENTLE DAILY SUPPORT


Mucomixx is a orodispersible lozenge designed for everyday oral care. Powered by the probiotic strain Levilactobacillus brevis CNCM I-5566 / DSM 27961, it works with your oral microbiome.

Why it matters

Oral pH balance: A balanced oral environment supports enamel care and everyday mouth comfort.
Microbiota-friendly approach: Formulated around a single, well-characterised strain used in clinical research.
On-the-go format: 20 convenient lozenges per pack; room-temperature stable.

What are you looking for?

Microbiota & gut (CDS22)

Microbiota & gut

Support, balance and regularity.

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Oral mucosa (Mucomixx)

Oral mucosa

Gum care and mouth comfort.

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Find your solution

Why you can trust

the inventor behind our lines.

All our products stem from the research of Professor Claudio De Simone (MD, FAGA), a leading figure in microbiota science.

With over 30 years of scientific backing, his exclusive formulations, like the renowned CDS22-formula (known in literature as the "De Simone Formulation" - DSF), are designed to support you with unmatched quality and precision.

Each product is developed with defined strains and precisely balanced compositions, following the scientific principles established by the inventor.

On drdesimone.net you can discover his original approach—carried forward with the same rigor, quality standards, and values.

We care about your order

INSULATED PACKAGING · ICE GEL PACKS · LIVE TRACKING · EXPRESS DELIVERY

Learn more about our Shipping Standards

Pack, cool & close (immediately before pickup!)

Pack, cool & close (immediately before pickup!)

We assemble your order from chilled stock, in specialized packaging + gel packs.
Parcel is sealed few minutes before DHL collects it, to minimise temperature swings and reduce idle time.
Hand-off to DHL

Hand-off to DHL

You receive live tracking at pickup, with options to change day/time or location.
Delivered to you in 1-2 business days

Delivered to you in 1-2 business days

Delivery times are indicative. Please check our Shipping Standards and Shipping Policy.

scientific insights

Stay Informed

Keep up-to-date with the latest research and developments in the field of probiotics and intestinal health. Our platform offers you exclusive scientific insights and updates directly from the research of Professor De Simone.

Our blog

Customer Support

We’re Here to Help

Have questions? Our dedicated support team is ready to assist you with your order. Contact us for personalized guidance and information.

Contact us at shop@drdesimone.net

F.A.Q.

Where can I buy your products?

You can purchase our products directly from drdesimone.net. However, in some regions, certain products may only be available through official local distributors. Please check our website for more details on availability in your area.

Are there any side effectsassociated with the De Simone Formulation (CDS22-formula)?

Although there are no significant risks associated with the use of CDS22-formula, the adaptation of the intestinal flora to the bacteria it contains may occasionally cause temporary abdominal bloating. In such cases, we recommend reducing the dosage for a few days.

How can I ensure I’m buying an authentic De Simone product?

Purchasing directly from DrDeSimone.net guarantees that you receive authentic products adhering to the original formulations created, developed and licensed by Prof. De Simone.

What is the De Simone Formulation?

The De Simone Formulation is a unique blend of specific bacterial strains developed by Prof. De Simone, extensively studied and recognized globally for its effectiveness in treating various intestinal health issues.

How do I know which product format is right for me?

Our products are available in different formats, including sachets and drops for infants, to meet diverse needs. Our customer support can help guide your choice based on your health requirements.

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    Our rigorous manufacturing standards and scientific backing ensure that you receive only the best probiotic formulations.

  • Live support

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